解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::A 97-year-old lady was hospitalized for left leg cellulitis. Comorbidity included hypertension and congestive heart failure. While in hospital, she developed a painless vesicular rash localized to the territory of the left trigeminal nerve (third branch), which evolved to pustules and crusts (Figure 1). A chickenpox-l...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-008-8287-5
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Individuals with end-stage renal disease (ESRD) are 10- to 25-fold more likely than immunocompetent people to develop active tuberculosis (TB) and are candidates for being treated for latent TB infection (LTBI). However, diagnosis using the tuberculin skin test (TST) is doubly difficult due to cutaneous aner...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-008-8082-3
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:The epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) has dramatically changed over the last decade by the emergence of community-associated MRSA (CA-MRSA). Recent studies indicate that these strains have already spread to hospitals. To evaluate if SCCmec type IV and Panton-Valentine leukoci...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-008-7430-7
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Reports on antibiotic use often lack complete definitions of the units of measurement, hampering the comparison of data between hospitals or hospital units. PATIENTS AND METHODS:To compare methods of measures of in-hospital antimicrobial use, we determined aggregate in-hospital consumption data at a tertiar...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-008-7462-z
更新日期:2008-12-01 00:00:00
abstract::Recently, important advances have been made in the immunodiagnosis of tuberculosis. New T cell interferon-gamma release assays (TIGRA) are more specific and more sensitive than the tuberculin skin test (TST) for the diagnosis of Mycobacterium tuberculosis (MTB) infection. However, like the TST, TIGRA are unable to dis...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-008-8089-9
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:In recent years, several reports have suggested, but never definitely demonstrated that dental units (DU) could be potential sources of viral cross-infections sustained by viral agents including HBV, HCV and HIV. This work aims at assessing the risk of HCV cross-infection by dental unit water lines (DUWLs). ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-008-7246-5
更新日期:2008-10-01 00:00:00
abstract:BACKGROUND:We examined lymphocyte apoptosis, activity of caspases-1, -3, -8 and -9 and the relationship between those two events and inflammation response in septic shock. MATERIALS AND METHODS:Blood samples were obtained within 24 h after diagnosis of septic shock from 16 patients to measure apoptosis, caspases-3, -8...
journal_title:Infection
pub_type: 信件
doi:10.1007/s15010-008-7070-y
更新日期:2008-10-01 00:00:00
abstract::We describe a 66-year-old woman hospitalized with fever, fatigue and hepatopathy. In her medical history arterial hypertension (treated with propranolol and lisinopril), diabetes mellitus type 2 (no treatment before admission) and a gout arthropathy were noted wherefore a therapy with allopurinol 300 mg per day has be...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6365-8
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:There is very less information on the use of antiretroviral (ARV) drugs and viro-immunological outcome over calendar years in Italy. PATIENTS AND METHODS:We performed an analysis of a prospective observational cohort (MASTER) to assess antiretroviral drug use in first line HAART and explore whether initial ...
journal_title:Infection
pub_type: 杂志文章,多中心研究
doi:10.1007/s15010-007-7227-0
更新日期:2008-06-01 00:00:00
abstract::A 47-year-old man with newly diagnosed acute myeloblastic leukemia and non-insulin-dependent diabetes mellitus developed Trichosporon asahii fungemia while receiving caspofungin as empirical antifungal therapy. The diagnosis was based on repeated isolation of T. asahii in culture of blood for three times. Despite trea...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6278-6
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Aspiration pneumonia (AP) and primary lung abscess (PLA), are diseases following aspiration of infectious material from the oropharynx or stomach. An antibiotic therapy, also covering anaerobic pathogens, is the treatment of choice. In this study we compared moxifloxacin (MXF) and ampicillin/sulbactam (AMP/S...
journal_title:Infection
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1007/s15010-007-7043-6
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:A retrospective study was conducted to provide epidemiological data on hospitalization for complicated and uncomplicated chickenpox in a pediatric population. METHODS:The study analyzed hospitalization cases for chickenpox, among all the 31 Tuscan hospitals, during the period 1997-2003. RESULTS:Globally, 6...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6248-z
更新日期:2007-12-01 00:00:00
abstract::The most efficient route of transmission of hepatitis C virus (HCV) infection is through contaminated blood. Sexual transmission or other close human contact could play a role in sporadic infections. We describe a case of acute hepatitis C progressing to chronic hepatitis over a follow-up of 4 years in a 44-year-old w...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-007-6188-7
更新日期:2007-12-01 00:00:00
abstract::Pulmonary edema is a recognized complication of Plasmodium falciparum malaria but is uncommon with Plasmodium vivax infection. We report the case of a non-immune adult with imported P. vivax malaria who developed pulmonary edema during treatment. The case was further complicated by a recurrent malaria episode after fa...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6108-x
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:This open, randomized, controlled study [208136/018] assessed the safety and immunogenicity of early vaccination with an experimental tetravalent measles-mumps-rubella-varicella (MMRV) vaccine (GlaxoSmithKline Biologicals) compared to concomitant administration of separate licensed MMR (Priorix) and varicell...
journal_title:Infection
pub_type: 杂志文章,随机对照试验
doi:10.1007/s15010-007-6337-z
更新日期:2007-10-01 00:00:00
abstract:INTRODUCTION:Influenza continues to be a considerable health problem in Europe. Vaccination is the only preventive measure, reducing mortality and morbidity of influenza in all age groups OBJECTIVES:The objective of this survey was to assess and compare the level of influenza vaccination coverage during three consecut...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6218-5
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:To prevent transmission of MRSA, eradication by antiseptic washings and nasal ointment is recommended. There are few studies, which investigated the success of eradication of MRSA carriage during everyday clinical working conditions and results are controversial. We wanted to assess the effectiveness of MRSA...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6273-y
更新日期:2007-06-01 00:00:00
abstract::Clinical features of liver involvement due to Listeria monocytogenes infection in adults are rarely reported in literature. This is surprising, regarding the current opinion that the portal system is extensively involved in the first stages of pathogenesis in invasive L. monocytogenes disease. A literature search in t...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-007-6006-2
更新日期:2007-06-01 00:00:00
abstract::A 67-year-old patient died of Legionella bozemanii pneumonia with negative urinary antigen and negative serology. Cystic lesions in pneumonia of unknown origin should lead to the differential diagnosis of L. bozemanii infections. ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6251-4
更新日期:2007-06-01 00:00:00
abstract:OBJECT:To assess easily monitored predictors for tuberculosis mortality. DESIGN:Risk factors for tuberculosis mortality were assessed during the 8-month treatment in 440 men and 269 women diagnosed with confirmed or presumed intrathoracic tuberculosis included prospectively in Guinea-Bissau from May 1996 to April 2001...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6090-3
更新日期:2007-04-01 00:00:00
abstract::Staphylococcus lugdunensis is a coagulase-negative Staphylococcus that causes skin and soft tissue infections and occasionally life threatening endocarditis of native valves. Prosthetic valve infection due to this pathogen is very rare and has not been described in HIV infected individuals. We report on the first case...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-007-6029-8
更新日期:2007-02-01 00:00:00
abstract:BACKGROUND:There are conflicting results concerning an association between Chlamydia pneumoniae and MS (multiple sclerosis). In the present study, we investigated a possible therapeutic option with antibiotics. PATIENTS AND METHODS:In our randomized, placebo-controlled double-blind study, 28 patients with the confirme...
journal_title:Infection
pub_type: 杂志文章,随机对照试验
doi:10.1007/s15010-006-5114-8
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Recently, two excellent methods have been used for the diagnosis of Legionnaires' disease: urinary antigen detection and PCR. The purpose of the present study is to analyze and evaluate the sensitivity and specificity of three different urinary antigen detection kits as well as PCR. MATERIALS AND METHODS:A ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-006-6639-6
更新日期:2006-10-01 00:00:00
abstract:BACKGROUND:Catheter-associated urinary tract infection is the most common nosocomial infection in clinical settings. For bacteria ascending to the bladder the most common route is the extraluminal, but the intraluminal route also plays a role. For this reason, we compared two urinary closed system bags (CSB), one with ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-006-5626-2
更新日期:2006-08-01 00:00:00
abstract:BACKGROUND:In recent years, the role of pro- and antiinflammatory cytokines in the development of Lyme arthritis (LA) has been widely discussed. The purpose of the present study was to determine the concentration of interleukin-18 (IL-18), interleukin-1beta (IL-beta) and its soluble receptor sIL-1RII in serum of patien...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-006-5013-z
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Screening for staphylococci among various patient populations has become important for appropriate therapeutic management and for control of nosocomial infections. The purpose of this study is to evaluate the in vitro sensitivity and specificity of a chromogenic agar medium, S. aureus ID (bioMérieux, France)...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-006-5094-8
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate the efficacy of sustained release of vancomycin and teicoplanin from a resorbable gelatin glycerol sponge, in order to establish a new delivery system for local anti-infective therapy. MATERIALS AND METHODS:60 plasticized glycerol gelatin sponges containing either 10 or...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-006-1067-1
更新日期:2006-02-01 00:00:00
abstract::Antibiotic activity against common respiratory pathogens can be affected by the pH of the medium (in vitro) or the bodily fluid (in vivo) in which bacteria are present. The ionized fraction of an antibiotic is not able to efficiently penetrate bacterial or mammalian membranes, reducing the quantity of molecules able t...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-005-8206-y
更新日期:2005-12-01 00:00:00
abstract:BACKGROUND:Blood cultures detect bacteremia in individual patients and help define local pathogen and resistance spectra. At the same time, the benefits of blood culture results in the management of individual patients -- and therefore their cost-effectiveness -- are disputed. PATIENTS AND METHODS:During 1 calendar ye...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-005-5065-5
更新日期:2005-10-01 00:00:00
abstract::Systemic enterococcal infections often lead to life-threatening disease. By analyzing the immune response of two patients with systemic enterococcal infections against enterococcal polysaccharide antigens, we found that both patients had antibodies against all four of the capsular serotypes identified to date. Antibod...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-005-5062-8
更新日期:2005-10-01 00:00:00
abstract::The case of an HIV-infected patient with low CD4+ cell count and localized pulmonary infection associated with Mycobacterium tilburgii, a recently recognized atypical mycobacterial species, is reported. Diagnosis was confirmed by repeated detection of mycobacterial DNA in lung biopsy specimens. After surgical removal ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-005-4118-0
更新日期:2005-08-01 00:00:00
abstract::The increasing resistance of Streptococcus pneumoniae, the most important community respiratory pathogen, to beta-lactams and other first-line antimicrobial agents usually employed for the empirical treatment of lower respiratory tract infections has led to the inclusion, in several current guidelines, of a fluoroquin...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-005-4102-8
更新日期:2005-06-01 00:00:00
abstract::Susceptibility to HIV-1 infections is, beside other factors, determined by individual host genetic variants like HLA class I alleles, CCR5 and CCR2 variants and levels of CCR5 binding chemokines. A new approach to determine the individual risk of acquiring an HIV infection or to estimate the disease progression could ...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-005-6305-4
更新日期:2005-06-01 00:00:00
abstract:INTRODUCTION:As the number of nosocomial methicillin-resistant Staphylococcus aureus (MRSA) infections in German intensive care units increases, the problem of MRSA infection as such is becoming ever more serious. The aim of this study was to investigate whether mortality rates from nosocomial MRSA pneumonia and primar...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-005-3186-5
更新日期:2005-04-01 00:00:00
abstract::Whipple's disease is a rare systemic disorder classically presenting with weight loss, arthralgias, and diarrhea, which was first described in 1907. The causative bacterium Tropheryma whipplei, is a fastidious organism not growing on conventional media. Before the introduction of polymerase chain reaction (PCR)-based ...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-005-4067-7
更新日期:2005-02-01 00:00:00
abstract::Staphylococcus aureus with resistance to glycopeptide antibiotics has been considered to be a rare cause of clinically relevant infections. A review of the current literature shows that this is indeed the case for infections caused by S. aureus with high-level resistance to vancomycin (VRSA), as only isolated cases ha...
journal_title:Infection
pub_type: 杂志文章,评审
doi:10.1007/s15010-004-4124-7
更新日期:2004-12-01 00:00:00
abstract::As highly active antiretroviral treatment (HAART) prolongs the life of HIV-infected individuals and reduces mortality associated with opportunistic infections, liver diseases have become a major challenge in the management of these patients. up to 45% of deaths of persons with HIV are related to endstage liver disease...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-004-6604-1
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:We compared standard antibiotic use with an antibiotic policy based on selective decontamination of the digestive tract (SDD) for cost and microbiology. PATIENTS AND METHODS:A 2-year before-after observational study was performed in an 11-bed, mixed medical and surgical intensive care unit (ICU). We include...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-004-3170-5
更新日期:2004-10-01 00:00:00
abstract:BACKGROUND:Due to insufficient vaccination rates, measles outbreaks still pose a threat to public health in Germany. The purpose of this study was to identify risk factors for undervaccination against measles. PATIENTS AND METHODS:Datasets from two cross-sectional surveys were analyzed by logistic regression models. T...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-004-3122-0
更新日期:2004-06-01 00:00:00
abstract::We describe two splenectomized patients admitted with pneumonia. The course in one was complicated by overwhelming multiorgan failure when the only indicative laboratory result was seropositivity for Legionella hackeliae and Legionella longbeachae. He was initially treated with ceftriaxone and roxithromycin, followed ...
journal_title:Infection
pub_type: 杂志文章
doi:10.1007/s15010-004-3005-4
更新日期:2004-06-01 00:00:00